UKTIS maintains information services for women and their healthcare providers.

We provide advice and information for health professionals via a dedicated telephone line, where pregnancy related enquiries can be discussed. Our opening hours are Monday to Friday 09:00 – 17:00. Outside of these hours, the service is available for urgent enquiries only.

UKTIS also produces full systematic evidence review documents on maternal exposures to drugs and chemicals which can be accessed by healthcare professionals via TOXBASE®.   Please visit to register — registration is free to NHS and NHS-affiliated departments, units and practices in the UK. Abstracts from our systematic reviews are freely available to the public via

UKTIS also provides free patient information leaflets on our BUMPs (‘best use of medicines in pregnancy’) website. This information for women and their families is based on the rigorous scientific material UKTIS produces for healthcare professionals. It can be accessed via

Research and surveillance

A key role of UKTIS is to conduct national surveillance, collecting pregnancy outcome data from women exposed to drugs and chemicals in pregnancy.  This generates prospective data on the incidence of fetal complications.  Such information is fundamental to expanding the limited available data on which to base an accurate individual risk assessment for a pregnant woman exposed to drugs and chemicals, and provide preconception advice for men and women exposed to drugs and chemicals. These data are included in UKTIS systematic evidence reviews and are also published in peer reviewed journals.

Further information can be obtained from our website,

Women can register their pregnancy online by visiting and creating a ‘my BUMPs’ record.