1. Causality
It does not matter if there is uncertainty about whether the reaction is associated with the medicine being taken. If it is suspected that there is an association then a yellow card should be completed.
In judging whether a patient may have had a reaction to the medicine they are taking, there are a number of factors which can be considered.

  •  Nature of the reaction
  •  Timing of the drug in relation to the reaction
  •  Reaction improves on withdrawal of the drug or dose reduction
  •  Reaction worsens on re-introduction of the drug

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