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Docusate for constipation

Medicines in Practice is a series of evidence–based publications specifically designed to support stakeholder medicines optimisation services. The series aims to maximise health gains through the optimum use of medicines, by influencing and changing prescribing behaviour. This document aims to review the evidence base for the use of docusate in the management of constipation, and […]

Pylera for the eradication of Helicobacter Pylori infection

Overview Medicines in Practice is a series of evidence–based publications specifically designed to support stakeholder medicines optimisation services. The series aims to maximise health gains through the optimum use of medicines, by influencing and changing prescribing behaviour. Pylera is a new triple fixed-dose combination capsule containing  bismuth, metronidazole and tetracycline.  In combination with omeprazole, it […]

Oral Sucralfate use in primary care

There have been concerns  raised previously about the safety profile and efficacy of sucralfate for long-term use.  The withdrawal of ranitidine from the UK marketplace in 2019, and subsequent concerns over the long-term use of proton pump inhibitors (PPIs) in certain patients have brought these concerns back in focus. This document aims to distil the […]

Optimised prescribing of oral iron supplements for iron deficiency anaemia

Iron deficiency anaemia (IDA) is estimated to affect 3% of men and 8% of women in the UK. Treatment involves addressing the underlying cause, and replenishing iron stores through iron replacement therapy. This document aims to outline the updated recommendations on dosing of oral iron supplements for IDA and their basis. It w also includes […]

Transfer of prescribing from private provider to NHS GP

This publication aims to provide guidance on what NHS prescribers need to be aware of when they are asked by a private healthcare provider, and/or patient, to take on the regular prescribing of a medication for a patient, including medicines supplied under formal shared care agreements. Based on suggested best practice it discusses the principles […]

Considerations for Sustainable Inhaler Prescribing

Inhalers account for approximately 3% of all NHS carbon emissions. Reducing the carbon impact from inhaler prescribing has been identified as a significant area of focus for delivering a net zero NHS. This document aims to outline strategies that can be considered to promote optimal respiratory care, while minimising the environmental impact from inhalers and […]

Optimising the use of morphine 10mg/5mL oral solution in primary care (Update)

Opioids are effective for acute pain and pain at the end of life, but there is little evidence of their effectiveness for long term pain. This document supports primary care teams to review patients receiving regular large quantities of morphine 10mg/5mL oral solution and includes advice on how these patients could be managed. This publication […]

Budesonide orodispersible tablets for maintenance of remission in eosinophilic oesophagitis

Budesonide orodispersible tablets (Jorveza) are indicated for induction and maintenance of remission in adults with eosinophilic oesophagitis. A NICE technology appraisal recommended budesonide ODT for induction of remission but did not address maintenance. This review assesses the evidence for use in maintenance treatment. Download the full review below to read more.

Cardiovascular outcomes associated with SGLT2 inhibitors (update 2)

The sodium-glucose co-transporter 2 (SGLT2) inhibitors canagliflozin, dapagliflozin, empagliflozin and ertugliflozin are licensed for the improvement of glycaemic control in adults with type 2 diabetes, a population at increased risk of cardiovascular events. Recent clinical trials and cohort studies have assessed whether the SGLT2 inhibitors reduce this risk. Download the full review below to read […]