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Safer Medication Use – Opioids and gabapentinoids

The use of combination opioids and gabapentinoids is associated with an increased risk of adverse events. Gabapentinoid overdose is much more likely to be fatal when combined with opioids and there is a greater risk of gabapentinoid dependence in patients with a history of opioid use disorder. There are limited circumstances when patients should be […]

Safer Medication Use – Ethanol in oral medicines for children

Ethanol is commonly used as an excipient in medicines, which is problematic in several patient groups but particularly so in children. The effects of chronic exposure to even small amounts of alcohol have not been well studied in children. In particular, phenobarbital elixir contains ethanol in such high amounts that children may ingest the equivalent […]