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Estradiol spray for the treatment of menopausal symptoms

New Drug Evaluations are concise, structured reviews of new drugs recently launched within the NHS. These documents seek to provide a brief overview of the efficacy, safety and cost of new drugs. Download the full review below to read more.

Fast acting insulin lispro for the treatment of diabetes mellitus

Overview New Drug Evaluations are concise, structured reviews of new drugs recently launched within the NHS. These documents seek to provide a brief overview of the efficacy, safety and cost of new drugs. Ultra-rapid acting insulin lispro (Lyumjev®▼, Lilly) is a new formulation of insulin lispro with added treprostinil and citrate to produce a more […]

Brolucizumab for wet age-related macular degeneration

Brolucizumab is a monoclonal antibody specific for vascular endothelial growth factor (VEGF). It is indicated for treatment of wet age-related macular degeneration (AMD), and is administered as an intravitreal injection every eight or 12 weeks. Download the full review below to read more.

Naldemedine for the treatment of opioid induced constipation

Naldemedine is the second oral peripherally acting μ-opioid receptor antagonist to be launched,after naloxegol. It is licensed for the treatment of opioid induced constipation (OIC) in adults whohave previously been treated with laxatives.

Pentosan for the treatment of bladder pain syndrome

Pentosan polysulfate sodium capsules (Elmiron®, Consilient Health) are indicated for the treatment of bladder pain syndrome characterised by glomerulations or Hunner’s lesions. Download the full review below to read more.

Melatonin prolonged-release (Slenyto) for insomnia in neurodevelopmental disorders

Melatonin prolonged-release tablets (Slenyto, Flynn Pharma) are the first oral melatonin formulation to be approved for use in children. Slenyto is indicated for the treatment of insomnia in children and adolescents (2 to 18 years old) with autism spectrum disorder (ASD) and/or Smith-Magenis syndrome (SMS), where sleep hygiene measures have been insufficient.