Overview

Medicines in Practice is a series of evidence–based publications specifically designed to support stakeholder medicines optimisation services. The series aims to maximise health gains through the optimum use of medicines, by influencing and changing prescribing behaviour.

There have been concerns  raised previously about the safety profile and efficacy of sucralfate for long-term use.  The withdrawal of ranitidine from the UK marketplace in 2019, and subsequent concerns over the long-term use of proton pump inhibitors (PPIs) in certain patients have brought these concerns back in focus. This document aims to distil the key evidence and recommendations regarding the use of oral sucralfate in primary care.